Mal-amido-PEG2-Val-Cit-PAB-PNP CAS#: 2112738-13-1

Mal-amido-PEG2-Val-Cit-PAB-PNP Basic information

Product Name:

Mal-amido-PEG2-Val-Cit-PAB-PNP

Synonyms:

Mal-amido-PEG2-Val-Cit-PAB-PNP
4-((2S,5S)-19-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-5-isopropyl-4,7,17-trioxo-2-(3-ureidopropyl)-10,13-dioxa-3,6,16-triazanonadecanamido)benzyl (4-nitrophenyl) carbonate

CAS:

2112738-13-1

MF:

C39H50N8O14

MW:

854.86

Product Categories:

ADC LINKER

Mol File:

2112738-13-1.mol

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Mal-amido-PEG2-Val-Cit-PAB-PNP Chemical Properties

storage temp.: Storage temp. -20°C
solubility: Soluble in DMSO, DCM, DMF
form: Solid
color: White to off-white

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Mal-amido-PEG2-Val-Cit-PAB-PNP Usage And Synthesis

Description

Mal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable ADC linker containing a maleimide group that can be reacted with thiol containing molecules.. The Val-Cit will specifically be cleaved by Cathepsin B.PNP can be substituted by nucleophiles.

Biological Activity

Mal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable ADC linker containing 2 units of PEG, which can be used to synthesize antibody drug conjugates (ADCs).

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Cleavable

Mal-amido-PEG2-Val-Cit-PAB-PNPSupplier

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Email: product02@bidepharm.com

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Email: psaitong@jm-bio.com

Nanjing Leon Biological Technology Co., Ltd.

Tel: 17705183659
Email: sales@njleonbiotech.com

Jiaxing Deyi Chemical Co., Ltd.

Tel: 86-0573-85866609 13325730825
Email: 945717149@qq.com

Aikon International Limited

Tel: 025-58859352 18068836627
Email: sales01@aikonchem.com

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