Mal-amido-PEG2-Val-Cit-PAB-PNP
Mal-amido-PEG2-Val-Cit-PAB-PNP Basic information
- Product Name:
- Mal-amido-PEG2-Val-Cit-PAB-PNP
- Synonyms:
-
- Mal-amido-PEG2-Val-Cit-PAB-PNP
- CAS:
- 2112738-13-1
- MF:
- C39H50N8O14
- MW:
- 854.86
- Product Categories:
-
- ADC LINKER
- Mol File:
- 2112738-13-1.mol
More
Less
Mal-amido-PEG2-Val-Cit-PAB-PNP Chemical Properties
- solubility
- Soluble in DMSO, DCM, DMF
- form
- Solid
- color
- White to off-white
More
Less
Mal-amido-PEG2-Val-Cit-PAB-PNP Usage And Synthesis
Description
Mal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable ADC linker containing a maleimide group that can be reacted with thiol containing molecules.. The Val-Cit will specifically be cleaved by Cathepsin B.PNP can be substituted by nucleophiles.
Biological Activity
Mal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable ADC linker containing 2 units of PEG, which can be used to synthesize antibody drug conjugates (ADCs).
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
| Cleavable
|
Mal-amido-PEG2-Val-Cit-PAB-PNPSupplier
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 18892239720
- psaitong@jm-bio.com
Nanjing Leon Biological Technology Co., Ltd.
- Tel
- 17705183659
- sales@njleonbiotech.com
Jiaxing Deyi Chemical Co., Ltd.
- Tel
- 0573-86-0573-85866609 13325730825
- 945717149@qq.com
Aikon International Limited
- Tel
- 025-58859352 18068836627
- sales01@aikonchem.com
Xi'an Confluore Biological Technology Co., Ltd.
- Tel
- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
More
Less
Mal-amido-PEG2-Val-Cit-PAB-PNP(2112738-13-1)Related Product Information
- Mal-amido-PEG9-DNP
- 4,7,10-Trioxa-13-azahexadecanoic acid, 16-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-14-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
- Mal-amido-PEG7-DNP
- Mal-amido-PEG6-DNP
- 4,7,10-Trioxa-13-azahexadecanoic acid, 16-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-14-oxo-
- INDEX NAME NOT YET ASSIGNED
- Mal-amido-PEG2-DNP
- Mal-amido-PEG2-Val-Cit-PAB-OH
- Mal-amido-PEG8-DNP