JQEZ5
JQEZ5 Basic information
- Product Name:
- JQEZ5
- Synonyms:
-
- JQEZ5
- JQ-EZ-05
- JQ-EZ-05 (JQEZ5)
- JQEZ5;JQE-Z5;JQE Z5
- CS-2764
- N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-pyrazolo[3,4-b]pyridine-4-carboxamide
- JQZ5
- 1H-Pyrazolo[3,4-b]pyridine-4-carboxamide, N-[(1,2-dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-
- CAS:
- 1913252-04-6
- MF:
- C30H38N8O2
- MW:
- 542.68
- Mol File:
- 1913252-04-6.mol
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JQEZ5 Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMSO:17.93(Max Conc. mg/mL);33.03(Max Conc. mM)
- form
- A crystalline solid
- color
- Light yellow to yellow
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JQEZ5 Usage And Synthesis
Uses
JQEZ5, is a novel and potent EZH2 inhibitor.
in vivo
JQEZ5 (75 mg/kg; intraperitoneal injection; daily; for 3 weeks) treatment exhibits rapid and pronounced tumor regression over the three week treatment course. And H3K27me3 levels are largely reduced with treatment further confirming the on-target effect of JQEZ5 in mice[1].
IC 50
EZH2
storage
Store at -20°C
JQEZ5Supplier
Sichuan Wei Keqi Biological Technology Co., Ltd.
- Tel
- 028-81700200 18116577057
- 3003855609@qq.com
Shanghai Lollane Biological Technology Co.,Ltd.
- Tel
- 021-52996696，15000506266 15000506266
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
ShangHai Biochempartner Co.,Ltd
- Tel
- 177-54423994 17754423994
- 2853530910@QQ.com
Beijing Solarbio Science & Tecnology Co., Ltd.
- Tel
- 010-50973130 18101056239
- 3193328036@qq.com