4-(3-CHLOROPHENYL)-ALPHA-(DIPHENYLMETHYL)-1-PIPERAZINEETHANOL HYDROCHLORIDE Chemical Properties

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO: >40 mg/mL

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/22-36/37/38

Safety Statements 

26-36-45

WGK Germany 

1

MSDS

• Language:English Provider:SigmaAldrich

4-(3-CHLOROPHENYL)-ALPHA-(DIPHENYLMETHYL)-1-PIPERAZINEETHANOL HYDROCHLORIDE Usage And Synthesis

Definition

ChEBI: 3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol is an N-alkylpiperazine that is 1-(3-chlorophenyl)piperazine carrying a 3,3-diphenyl-2-hydroxyprop-1-yl group at position 4. A selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B, and exhibiting little or no affinity for a range of other receptor types. It has a role as a serotonergic antagonist and a geroprotector. It is a N-alkylpiperazine, a N-arylpiperazine, a secondary alcohol and a member of monochlorobenzenes. It is a conjugate base of a 4-(3-chlorophenyl)-1-(2-hydroxy-3,3-diphenylpropyl)piperazin-1-ium(1+).