FMOC-MET(O2)-OH
FMOC-MET(O2)-OH Basic information
- Product Name:
- FMOC-MET(O2)-OH
- Synonyms:
-
- FMOC-L-METHIONINE-SULFONE
- FMOC-L-MET(O2)-OH
- FMOC-METHIONINE(O2)-OH
- FMOC-MET(O2)-OH
- (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-(methylsulfonyl)butanoic acid
- FMoc-Met(O)2-OH FMoc-L-Methionine sulfone
- N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-METHIONINE SULFONE
- N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-METHIONINESULFON
- CAS:
- 163437-14-7
- MF:
- C20H21NO6S
- MW:
- 403.45
- Mol File:
- 163437-14-7.mol
FMOC-MET(O2)-OH Chemical Properties
- Boiling point:
- 709.5±60.0 °C(Predicted)
- Density
- 1.359
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- pka
- 3.52±0.10(Predicted)
- form
- Powder
- color
- White
- InChIKey
- KJLKPACOHZKRFM-SFHVURJKSA-N
- CAS DataBase Reference
- 163437-14-7(CAS DataBase Reference)
FMOC-MET(O2)-OH Usage And Synthesis
Description
FMOC-Met (O2)-OH is the N-alpha protected form of L-methionine mediated by FMOC group (9-Fluorenylmethyloxycarbonyl). It is useful to act as a building block in peptide synthesis. For example, it, as well as its derivative Tbfmoc-Met-OH can be used as a building block for the solid phase synthesis of ubiquitin C-hydrazide. It can also be used for synthesizing some novel cyclic peptides with pharmacological effects such as treatment of inflammatory disease.
Chemical Properties
White powder
References
http://www.sigmaaldrich.com/technical-documents/articles/chemfiles/natural-amino-acid.html
https://www.iris-biotech.de/de/faa1490/Anderson, S. N., et al. "Microarrayed compound screening (microARCS) to identify activators and inhibitors of AMP-activated protein kinase."Journal of Biomolecular Screening 9.2(2004):112-121.
http://web.b.ebscohost.com/abstract?direct=true&profile=ehost&scope=site&authtype=crawler&jrnl=09707077&AN=103358230&=iEFjDXbrcrGANWWK7vpLdmsN8yhCmNraNdm1aLMwCgXjuCpr9xSGhioVTsYZqXmo5JtrShPp2WNBkVHpx75ovQ%3d%3d&crl=c&resultNs=AdminWebAuth&resultLocal=ErrCrlNotAuth&crlhashurl=login.aspx%3fdirect%3dtrue%26profile%3dehost%26scope%3dsite%26authtype%3dcrawler%26jrnl%3d09707077%26AN%3d103358230
http://www.google.com/patents/US6511961
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