STIGMATELLIN
STIGMATELLIN Basic information
- Product Name:
- STIGMATELLIN
- Synonyms:
-
- 2-(4,6-Dimethoxy-3,5,11-trimethyl-7,9,11-tridecatrienyl)-8-hydroxy-5,7-dimethoxy-3-methyl-4H-1-benzopyran-4-one
- STIGMATELLIN
- (e,e,e)-)-8-hydroxy-3-methyl
- chromone,5,7-dimethoxy-2-(4,6-dimethoxy-3,5,11-trimethyl-7,9,11-tridecatrienyl
- 4H-1-Benzopyran-4-one, 2-(4,6-dimethoxy-3,5,11-trimethyl-7,9,11-tridecatrien-1-yl)-8-hydroxy-5,7-dimethoxy-3-methyl-
- Stigmatellin DISCONTINUED. Please see S686780.
- CAS:
- 91682-96-1
- MF:
- C30H42O7
- MW:
- 514.65
- Product Categories:
-
- Antibiotics
- Antibiotics A to
- Antibiotics by Application
- Antibiotics N-SAntibiotics
- AntifungalAntibiotics
- Antineoplastic and Immunosuppressive AntibioticsAntibiotics
- Chemical Structure Class
- Inhibits an EnzymeAntibiotics
- Mechanism of Action
- Miscellaneous
- Spectrum of Activity
- Mol File:
- 91682-96-1.mol
STIGMATELLIN Chemical Properties
- Melting point:
- 129°C
- Boiling point:
- 520.22°C (rough estimate)
- Density
- 1.0924 (rough estimate)
- refractive index
- 1.5800 (estimate)
- storage temp.
- −20°C
- pka
- 8.67±0.40(Predicted)
MSDS
- Language:English Provider:SigmaAldrich
STIGMATELLIN Usage And Synthesis
Uses
Stigmatellin is a cytochrome bc1 complex inhibitor.
Definition
ChEBI: A member of the class of chromones that is isolated from Stigmatella aurantiaca Sg a15.
Purification Methods
Stigmatellin A is stable in aqueous solution at neutral pH but decomposes at pH <5. It is purified by recrystallisation from toluene/hexane. It has UV max: nm () 248sh (4,100), 258 (59,500), 267 (65,500)max: 3550m, 1645chs, 1635ss, 1620ss, 1590s, 1510m and 905m cm-1. It gives colour reactions at 110o with vanillin/H2SO4 (grey), Ce(IV)/(NH4)2SO4 (yellow) and phosphomolybdate (blue-grey). [H.fle et al. Justus Liebigs Ann Chem 1882 1984.] It inhibits electron transport [Jagow & Link Methods Enzymol 126 253 1986, Robertson et al. Biochemistry 32 1310 1933], and has antibiotic properties [Kunze et al. J Antibiot 37 454 1984]. The 7t,9t,11c-isomer is Stigmatellin B.
STIGMATELLIN(91682-96-1)Related Product Information
- CHROMONE
- 2'-pentyloxyacetophenone
- 2,4,6-Trimethoxyphenol
- Maltoryzine
- 2',5'-DIHYDROXYPROPIOPHENONE
- 2,6-Dimethoxyhydroquinone
- 8,10-DODECADIEN-1-OL
- STIGMATELLIN
- 3,6-DIHYDROXY-2,4-DIMETHOXYACETOPHENONE
- 5,7-DIMETHOXY-2-METHYL-CHROMEN-4-ONE
- 2,4,6-Trimethoxybenzaldehyde
- 2-N-HEXYLOXYBENZALDEHYDE
- 3-(2-METHOXYPHENYL)-2-METHYL-1-PROPENE