Basic information Safety Supplier Related

3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE

Basic information Safety Supplier Related

3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE Basic information

Product Name:
3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE
Synonyms:
  • FURAFYLLINE
  • 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE
  • Furafylline,3-(2-Furanylmethyl)-3,7-dihydro-1,8-dimethyl-1H-purine-2,6-dione
  • FURAFYLLINE INHIBITOR OF CYTOCHRO
  • 1H-Purine-2,6-dione, 3-(2-furanylmethyl)-3,9-dihydro-1,8-dimethyl-
  • 3-(Furan-2-ylmethyl)-1,8-dimethyl-1H-purine-2,6(3H,7H)-dione
  • Cytochrome P450,inhibit,Inhibitor,CYPs,Furafylline
  • Furatheophylline
CAS:
80288-49-9
MF:
C12H12N4O3
MW:
260.25
EINECS:
200-158-5
Mol File:
80288-49-9.mol
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3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE Chemical Properties

Melting point:
>162°C (dec.)
Boiling point:
543.6±60.0 °C(Predicted)
Density 
1.443±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
solubility 
ethanol: 0.33 mg/mL
form 
solid
pka
8.62±0.70(Predicted)
color 
white
InChIKey
KGQZGCIVHYLPBH-UHFFFAOYSA-N
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Safety Information

WGK Germany 
3

MSDS

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3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE Usage And Synthesis

Uses

Furafylline is a selective inhibitor of human cytochrome P450. It is also reported to inhibit the oxidation of caffeine.

Definition

ChEBI: Furafylline is an oxopurine.

Biochem/physiol Actions

Furafylline (1,8-dimethyl-3-(2′ -furfuryl)methylxanthine) is a xanthine derivative. It is preferred in treating asthma. It serves as a N3-demethylation inhibitor of caffeine. Furafylline does not show much effect on human monooxygenase activities. It is considered as an efficient bronchodilator and as an inhibitor of anaphylactic reactions, when compared to theophylline.

3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONESupplier

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