3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE
3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE Basic information
- Product Name:
- 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE
- Synonyms:
-
- FURAFYLLINE
- 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE
- Furafylline,3-(2-Furanylmethyl)-3,7-dihydro-1,8-dimethyl-1H-purine-2,6-dione
- FURAFYLLINE INHIBITOR OF CYTOCHRO
- 1H-Purine-2,6-dione, 3-(2-furanylmethyl)-3,9-dihydro-1,8-dimethyl-
- 3-(Furan-2-ylmethyl)-1,8-dimethyl-1H-purine-2,6(3H,7H)-dione
- Cytochrome P450,inhibit,Inhibitor,CYPs,Furafylline
- Furatheophylline
- CAS:
- 80288-49-9
- MF:
- C12H12N4O3
- MW:
- 260.25
- EINECS:
- 200-158-5
- Mol File:
- 80288-49-9.mol
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3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE Chemical Properties
- Melting point:
- >162°C (dec.)
- Boiling point:
- 543.6±60.0 °C(Predicted)
- Density
- 1.443±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- solubility
- ethanol: 0.33 mg/mL
- form
- solid
- pka
- 8.62±0.70(Predicted)
- color
- white
- InChIKey
- KGQZGCIVHYLPBH-UHFFFAOYSA-N
MSDS
- Language:English Provider:SigmaAldrich
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3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE Usage And Synthesis
Uses
Furafylline is a selective inhibitor of human cytochrome P450. It is also reported to inhibit the oxidation of caffeine.
Definition
ChEBI: Furafylline is an oxopurine.
Biochem/physiol Actions
Furafylline (1,8-dimethyl-3-(2′ -furfuryl)methylxanthine) is a xanthine derivative. It is preferred in treating asthma. It serves as a N3-demethylation inhibitor of caffeine. Furafylline does not show much effect on human monooxygenase activities. It is considered as an efficient bronchodilator and as an inhibitor of anaphylactic reactions, when compared to theophylline.
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