FTBMT
FTBMT Basic information
- Product Name:
- FTBMT
- Synonyms:
-
- FTBMT
- Benzamide, 4-[3-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-5-methyl-1H-1,2,4-triazol-1-yl]-2-methyl-
- FTBMT >=98% (HPLC)
- 4-(3-{[3-fluoro-5-(trifluoromethyl)phenyl]methyl}-5 -methyl-1H-1,2,4-triazol-1-yl)-2-methylbenzamide
- inhibit,FTBMT,Inhibitor
- TP-024
- 4-(3-(3-Fluoro-5-(trifluoromethyl)benzyl)-5-methyl-1H-1,2,4-triazol-1-yl)-2-methylbenzamide
- FTBMT, 10 mM in DMSO
- CAS:
- 1358575-02-6
- MF:
- C19H16F4N4O
- MW:
- 392.35
- Mol File:
- 1358575-02-6.mol
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FTBMT Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMSO:69.62(Max Conc. mg/mL);177.44(Max Conc. mM)
- form
- Solid
- color
- Light yellow to orange
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FTBMT Usage And Synthesis
Uses
FTBMT is a GPR52 receptor agonist with an EC50 value of 71 nM. Studies demonstrate antipsychotic-like effects of FTBMT in murine models of schizophrenia. FTBMT elicits beneficial effects on cognitive processes such as spatial working memory and long-term memory in mice.
Biological Activity
FTBMT is an orally available, selective and potent agonist of GPR52. It exhibits antipsychotic and procognitive properties without causing catalepsy in rodents. FTBMT improves recognition memory in a novel object recognition test and mitigates MK-801-induced working memory deficits in a radial arm maze test in rats.
storage
Store at -20°C
FTBMTSupplier
BOC Sciences
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- 16314854226
- info@bocsci.com
Shanghai EFE Biological Technology Co., Ltd.
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- 021-65675885 18964387627
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ShangHai Biochempartner Co.,Ltd
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- 17754423994 17754423994
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Shanghai Chaolan Chemical Technology Center
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- 021-QQ：65489617 15618227136
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Chuzhou KeMail Chemical Technology Co., Ltd
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- 0550-5196001 15000891977
- wj520wjxby@126.com