5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl) adenosine
5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl) adenosine Basic information
- Product Name:
- 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl) adenosine
- Synonyms:
-
- 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl) adenosine
- 2'-O-(2-Methoxyethyl)-5'-O-bis(4-methoxyphenyl)phenylmethyladenosine
- Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-
- 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)adenosine
- (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol
- (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-(2-methoxyethoxy)oxolan-3-ol
- CAS:
- 1384253-67-1
- MF:
- C34H37N5O7
- MW:
- 627.69
- Mol File:
- 1384253-67-1.mol
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5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl) adenosine Chemical Properties
- Boiling point:
- 821.6±75.0 °C(Predicted)
- Density
- 1.34±0.1 g/cm3(Predicted)
- pka
- 13.07±0.70(Predicted)
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5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl) adenosine Usage And Synthesis
Uses
5’-O-(4,4’-Dimethoxytrityl)-2’-O-(2-methoxyethyl) adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
References
[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
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