1,1'-Carbonyl-di(1,2,4-triazole) Chemical Properties

Melting point:

145-150 °C

Boiling point:

429.1±28.0 °C(Predicted)

Density 

1.75±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Chloroform (Slightly), DMSO (Sparingly, Heated)

form 

Solid

pka

-0.26±0.10(Predicted)

color 

White to Off-White

BRN 

10250

Stability:

Hygroscopic, Moisture Sensitive

Safety Information

Hazard Codes 

Xn

Risk Statements 

63-22-41-52/53-62-61

Safety Statements 

22-26-36/37/39-61-36/39

WGK Germany 

3

F 

10-21

HS Code 

29339900

MSDS

• Language:English Provider:SigmaAldrich

1,1'-Carbonyl-di(1,2,4-triazole) Usage And Synthesis

Chemical Properties

1,1'-Carbonyl-di(1,2,4-triazole) is beige powder

Uses

1,1'-Carbonyl-di(1,2,4-triazole) is used in epoxidation reactions in organic synthesis. It is useful in preparing acyl triazolides from carboxylic acids. 1'-Carbonyl-di(1,2,4-triazole) is a reagent for peptide synthesis; preparation of thiol or selenol esters.

Uses

N,N''-Carbonyl-di-(1,2,4-triazole) is used in preparation of the bridged cycloformylpyridine derivative and their medical applications.

reaction suitability

reaction type: Carbonylations

Synthesis

1,1'-Carbonyl-di(1,2,4-triazole) is preparate from triazole and phosgene in THF, in the presence of one equivalent of pyridine (80% yield)[1-2].

Precautions

It may be stored in a desiccator over P2O5 at room temperature for many months without apparent decomposition.

References

1. Beyerman, H. C.; Van Den Brink, W. M. RTC 1961, 80, 1372.
2. Gais, H.-J. AG(E) 1977, 16, 244.

1,1'-Carbonyl-di(1,2,4-triazole)(41864-22-6)Related Product Information

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• 1,1'-Carbonyl-di(1,2,4-triazole)