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10-Deacetyl Paclitaxel Ethyl Analogue

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10-Deacetyl Paclitaxel Ethyl Analogue Basic information

Product Name:
10-Deacetyl Paclitaxel Ethyl Analogue
Synonyms:
  • 10-Deacetyl Paclitaxel Ethyl Analogue
  • 10-Deacetyl-3’-debenzoyl-3’-propanoylpaclitaxel
  • Paclitaxel impurity 4/10-Deacetyl Paclitaxel Ethyl Analogue/N-Debenzoyl-N-propanoyl-10-deacetylpaclitaxel/(2aR,4S,4aS,6R,9S,11S,12S, 12aR,12bS)-12b-Acetoxy-4,6,11-trihydroxy-9-(((2R,3S)-2-hydroxy-3-phenyl-3-propionamidopropanoyl)oxy)-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl Benzoate
  • Paclitaxel impurity 4/10-Deacetyl Paclitaxel Ethyl Analogue/N-Debenzoyl-N-propanoyl-10-deacetylpaclitaxel
  • Benzenepropanoic acid, α-hydroxy-β-[(1-oxopropyl)amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
  • 10-Deacetyl Ethyl Paclitaxel
  • 10-Deacetylated paclitaxel ethyl ester analogue
  • Docetaxel Impurity 60 (10-Deacetyl Paclitaxel Ethyl Analogue)
CAS:
173101-59-2
MF:
C41H49NO13
MW:
763.84
Mol File:
173101-59-2.mol
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10-Deacetyl Paclitaxel Ethyl Analogue Chemical Properties

Boiling point:
916.3±65.0 °C(Predicted)
Density 
1.39±0.1 g/cm3(Predicted)
pka
11.31±0.70(Predicted)
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10-Deacetyl Paclitaxel Ethyl Analogue Usage And Synthesis

Uses

N-Debenzoyl-N-propanoyl-10-deacetylpaclitaxel is an impurity of Paclitaxel (P132500); an antineoplastic. Used in the study of structure and function of microtubules into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast, head and neck cancer, and advanced forms of Kaposi''s sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy.

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