(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Chemical Properties

Melting point:

100-104 °C(Solv: ligroine (8032-32-4))

Boiling point:

411.7±45.0 °C(Predicted)

Density 

1.328±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,2-8°C

solubility 

DMSO: ~13 mg/mL

form 

solid

pka

-1.36±0.13(Predicted)

color 

yellow

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Usage And Synthesis

Uses

PD 81,723 is an allosteric potentiator that increases the functional effects of adenosine and adenosine analogs.

Biological Activity

Allosteric potentiator at the adenosine A 1 receptor; acts via agonist-dependent and -independent mechanisms. Enhances agonist affinity for, and increased t 1/2 of dissociation from, the receptor. Also inhibits basal and forskolin-stimulated adenylyl cyclase (AC) activity in A 1 receptors expressed in CHO cells, possibly via direct potentiation of constitutive receptor activity or by direct inhibition of AC. Active in vivo .

storage

Store at RT

(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE(132861-87-1)Related Product Information

• 3-(3-TRIFLUOROMETHYLBENZOYL)THIOPHENE
• 3-(3-METHYLBENZOYL)THIOPHENE
• (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE
• 3-BENZOYLTHIOPHENE
• (2-Amino-3-thienyl)(phenyl)methanone
• 2-AMINO-3-BENZOYL-4,5-DIMETHYLTHIOPHENE