2,2-DIPHENYLETHYL ISOTHIOCYANATE
2,2-DIPHENYLETHYL ISOTHIOCYANATE Basic information
- Product Name:
- 2,2-DIPHENYLETHYL ISOTHIOCYANATE
- Synonyms:
-
- 2,2-DIPHENYLETHYL ISOTHIOCYANATE
- 2,2-Diphenylethyl isothiocyate, 98%
- SF 5
- SF5
- SF-5
- SF5, 10 mM in DMSO
- CAS:
- 34634-22-5
- MF:
- C15H13NS
- MW:
- 239.34
- Mol File:
- 34634-22-5.mol
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2,2-DIPHENYLETHYL ISOTHIOCYANATE Chemical Properties
- Melting point:
- 36 °C
- Boiling point:
- 160 °C
- form
- Solid
- color
- White to off-white
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Safety Information
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36/37/39
- RIDADR
- 2811
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2,2-DIPHENYLETHYL ISOTHIOCYANATE Usage And Synthesis
Uses
SF5 (2,2-Diphenylethyl isothiocyanate) is a sulforaphane analog. SF5 inhibits apoptosis by the JNK-p53-caspase pathway. SF5 can be used as a new renal protective agent for drug-resistant acute renal disease[1].
References
[1] Kim T, et al. The synthesis of sulforaphane analogues and their protection effect against cisplatin induced cytotoxicity in kidney cells. Bioorg Med Chem Lett. 2015 Jan 1;25(1):62-6. DOI:10.1016/j.bmcl.2014.11.014
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