7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE CAS#: 75187-63-2

7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE Basic information

Product Name:

7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE

Synonyms:

7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE
4',7,8-Trihydroxy isoflavone
7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE 98%
YN1
7,8-dihydroxy-3-(4-hydroxyphenyl)-4h-chroMen-4-one
4H-1-Benzopyran-4-one,7,8-dihydroxy-3-(4-hydroxyphenyl)-
YN1 >=98% (HPLC)
7,8-Dihydroxy-3-(4-hydroxy-pheny

CAS:

75187-63-2

MF:

C15H10O5

MW:

270.24

Mol File:

75187-63-2.mol

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7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE Chemical Properties

storage temp.: 2-8°C
solubility: DMSO: soluble10mg/mL, clear
form: powder
color: white to beige

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Safety Information

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3
HS Code: 2932990090

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7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE Usage And Synthesis

Definition

ChEBI: 8-Hydroxydaidzein is a member of isoflavones.

Biochem/physiol Actions

YN1 is a potent inhibitor of PFKFB3 (6-Phosphfructo-2-kinase/fructose-2,6-bisphosphatase: IC50 = 670 nM). PFKFB3 is over expressed in many cancers, and catalyzes the production of fructose-2,6-bisphosphate, which can potentiate PFK1 activity, enhancing glycolysis in tumor cells. YN1 inhibits glycolysis and proliferation in HeLa cells.

7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONESupplier

J & K SCIENTIFIC LTD.

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Bide Pharmatech Ltd.

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Sigma-Aldrich

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Chengdu DingDang Pharmaceutical Co., Ltd.

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Email: market@dingdangchem.com

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