PYR-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2 Chemical Properties

Boiling point:

1638.4±65.0 °C(Predicted)

Density 

1.374±0.06 g/cm3(Predicted)

storage temp. 

−20°C

solubility 

Soluble to 2 mg/ml in DMSO

pka

13.12±0.20(Predicted)

Sequence

{Glp}-Gln-Trp-Phe-Trp-Trp-Met-NH2

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

PYR-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2 Usage And Synthesis

Uses

G-Protein antagonist peptide is the substance P-related peptide that inhibits binding of G proteins to their receptors. G-Protein antagonist peptide competitively and reversibly inhibits M2 muscarinic receptor activation of Gi or Go and inhibits Gs activation by β-adrenoceptors.

References

[1] Mukai H, et al. G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding. J Biol Chem. 1992;267(23):16237-16243. PMID:1379592

PYR-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2(143675-79-0)Related Product Information

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