1H-Pyrrolo[1,2-a]indole-1-acetic acid, 9-[(4-chlorophenyl)thio]-6-fluoro-2,3-dihydro-, (1R)- Chemical Properties

Boiling point:

583.8±50.0 °C(Predicted)

Density 

1.46±0.1 g/cm3(Predicted)

pka

4.53±0.10(Predicted)

form 

Solid

color 

Light yellow to yellow

1H-Pyrrolo[1,2-a]indole-1-acetic acid, 9-[(4-chlorophenyl)thio]-6-fluoro-2,3-dihydro-, (1R)- Usage And Synthesis

Uses

(R)-L 888607 is the isomer of L 888607 (HY-111271), and can be used as an experimental control. L 888607 is a potent, selective, stable and orally active CRTH2 agonist. L 888607 has high affinity for the human CRTH2 receptor with a Ki value of 4 nM. L 888607 can be used for the research of several physiological events and metabolite[1].

References

[1] Gervais FG, Identification of a potent and selective synthetic agonist at the CRTH2 receptor. Mol Pharmacol. 2005 Jun;67(6):1834-9. DOI:10.1124/mol.104.009068