Nicotine hydrochloride Chemical Properties

EPA Substance Registry System

Pyridine, 3-[(2S)-1-methyl-2-pyrrolidinyl]-, hydrochloride (2820-51-1)

Safety Information

RIDADR 

1656

HazardClass 

6.1(a)

PackingGroup 

II

Hazardous Substances Data

2820-51-1(Hazardous Substances Data)

Toxicity

guinea pig,LDLo,intraperitoneal,32mg/kg (32mg/kg),BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLDLUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION,Australian Journal of Experimental Biology and Medical Science. Vol. 25, Pg. 83, 1947.

Nicotine hydrochloride Usage And Synthesis

General Description

A white crystalline solid. Combustible, although ignition may be difficult. Toxic by inhalation (dust, etc.) and skin absorption. Produces toxic oxides of nitrogen during combustion.

Air & Water Reactions

Soluble in water.

Reactivity Profile

The chloride salt of nicotine-An alkaloid produced from tobacco. Colorless, oily liquid, combustible, highly toxic. When heated to decomposition Nicotine hydrochloride emits very toxic fumes of carbon monoxide and oxides of nitrogen [Lewis, 3rd ed., 1993, p. 919].

Health Hazard

Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Containers may explode when heated. Runoff may pollute waterways.

Safety Profile

Poison by intravenous, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of Cl-, NOx, and CO. See also NICOTINE.