metipranolol Chemical Properties

Melting point:

105-107℃

Boiling point:

458.7±45.0 °C(Predicted)

Density 

1.068

storage temp. 

4°C, protect from light

solubility 

DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:6): 0.14 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml

form 

A crystalline solid

pka

13.91±0.20(Predicted)

Safety Information

Toxicity

LD50 in mice (mg/kg): 31 i.v. (Bartsch)

metipranolol Usage And Synthesis

Uses

Antihypertensive (β-blocker, ophthalmic).

Definition

ChEBI: 3-(Propan-2-ylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is substituted by a 4-acetoxy-2,3,5-trimethylphenoxy group. A non-cardioselective beta-blocker, it is used to lower intra-ocular pressure in the management of open-angl glaucoma.

brand name

OptiPranolol (Bausch & Lomb Pharmaceuticals).

metipranolol(22664-55-7)Related Product Information

• 2,3,6-Trimethylphenol
• MetipranololHydrochloride
• metipranolol
• SALOR-INT L128228-1EA
• SALOR-INT L129194-1EA
• SALOR-INT L129933-1EA
• SALOR-INT L129070-1EA