N'-benzylpivalohydrazide
N'-benzylpivalohydrazide Basic information
- Product Name:
- N'-benzylpivalohydrazide
- Synonyms:
-
- N'-benzylpivalohydrazide
- pivalylbenzhydrazine
- 2,2-Dimethyl-N'-(phenylmethyl)propanoic acid hydrazide
- Angorvit
- Ro 4-1634
- 2,2-Dimethylpropanoic acid 2-(phenylmethyl)hydrazide
- 2971-75-7 (Hydrochloride)
- Betamezid
- CAS:
- 306-19-4
- MF:
- C12H18N2O
- MW:
- 206.28
- EINECS:
- 206-180-9
- Mol File:
- 306-19-4.mol
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N'-benzylpivalohydrazide Chemical Properties
- Melting point:
- 68-69°
- Boiling point:
- 296.1±23.0 °C(Predicted)
- Density
- 1.015±0.06 g/cm3(Predicted)
- pka
- 13.41±0.50(Predicted)
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N'-benzylpivalohydrazide Usage And Synthesis
Uses
Pivalylbenzhydrazine (Pivhydrazine) is a potent monoamine oxidase (MAO) inhibitor. Pivalylbenzhydrazine decreases cartilage growth in normal rats. Pivalylbenzhydrazine can be used in research of depression[1].
Definition
ChEBI: Pivhydrazine is a member of benzenes.
in vivo
Pivalylbenzhydrazine (Pivhydrazine; 5 mg/kg; i.p.; daily, for 5 d; immature female rats) inhibits the growth of the epiphysial cartilage[1].
| Animal Model: | Immature female rats (40 g, 3-4 weeks age)[1] |
| Dosage: | 5 mg/kg |
| Administration: | Intraperitoneal injection; daily, for 5 days |
| Result: | Inhibited the growth of the epiphysial cartilage |
References
[1] Zor U, et, al. The effect of monoamine oxidase inhibitors on growth and the rat tibia test. J Endocrinol. 1965 Apr;32:35-43. DOI:10.1677/joe.0.0320035
N'-benzylpivalohydrazide Supplier
Shanghai Nafu Biotechnology Co., Ltd.
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Guangdong Wengjiang Chemical Reagent Co., Ltd.
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Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
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TargetMol Chemicals Inc.
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Shaoguan Qicheng Biotechnology Co., Ltd
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- 18122215013
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