Basic information Safety Supplier Related

cotarnine

Basic information Safety Supplier Related

cotarnine Basic information

Product Name:
cotarnine
Synonyms:
  • 1,3-Dioxolo(4,5-g)isoquinolin-5-ol, 5,6,7,8-tetrahydro-4-methoxy-6-methyl- (9CI)
  • 4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-ol
  • Cotarnine (base and/or unspecified salts)
  • cotarnin
  • 1-Hydroxy-8-methoxy-2-methyl-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinoline
  • 4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-ol
  • Noscapine Impurity 1(Cotarnine)
  • 6-methyl-5-hydroxy-4-methoxy-5,6,7,8-tetrahydro-2H-1,3-methylenedioxy-[4,5-g]isoquinoline
CAS:
82-54-2
MF:
C12H15NO4
MW:
237.25
EINECS:
201-429-8
Mol File:
82-54-2.mol
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cotarnine Chemical Properties

Melting point:
132.5°C (rough estimate)
Boiling point:
379.78°C (rough estimate)
Density 
1.2026 (rough estimate)
refractive index 
1.5200 (estimate)
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
12.82±0.20(Predicted)
color 
Light Yellow to Yellow
Stability:
Hygroscopic
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Safety Information

RIDADR 
1544
HazardClass 
6.1(a)
PackingGroup 
II
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cotarnine Usage And Synthesis

Uses

Cotarnine is an intermediate in synthesizing Cotarnine Chloride (C717500), an oxidative degradation product of the drug Noscapine.

Definition

ChEBI: Cotarnine is a member of isoquinolines.

cotarnineSupplier

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