Basic information Safety Supplier Related

fluphenazine O-enantate

Basic information Safety Supplier Related

fluphenazine O-enantate Basic information

Product Name:
fluphenazine O-enantate
Synonyms:
  • fluphenazine O-enantate
  • Heptanoic acid, 2-4-3-2-(trifluoromethyl)-10H-phenothiazin-10-ylpropyl-1-piperazinylethyl ester
  • moditen enanthate
  • 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl heptanoate
  • enanthic acid 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl ester
  • 2-[4-[3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl]-1-piperazinyl]ethyl heptanoate
  • Fluphenazine enantate CRS
  • Fluphenazine Decanoate Impurity 3 (Fluphenazine Decanoate EP Impurity C)
CAS:
2746-81-8
MF:
C29H38F3N3O2S
MW:
549.698
EINECS:
2203850
Product Categories:
  • Organics
Mol File:
2746-81-8.mol
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fluphenazine O-enantate Chemical Properties

Melting point:
184.5°C
Boiling point:
629.4±55.0 °C(Predicted)
Density 
1.1661 (estimate)
storage temp. 
2-8°C
solubility 
Practically insoluble in water, very soluble in ethanol and in methylene chloride, freely soluble in methanol.
pka
7.32±0.10(Predicted)
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Safety Information

RIDADR 
3249
HazardClass 
6.1(b)
PackingGroup 
III
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fluphenazine O-enantate Usage And Synthesis

Chemical Properties

Pale yellow, viscous liquid or yellow solid.

Uses

Fluphenazine Enanthate serves as a medication for the treatment of tardive dyskinesia (TD) in monkeys. Fluphenazine Enanthate also functions as a medication for the antipsychotics study on human prolactin levels. Fluphenazine Enanthate reduces the blood pressure of pentobarbital Na anesthetized dogs, reduces heart rate in anesthetized dogs, and increases coronary blood flow and femoral blood flow in anesthetized dogs enhancing cardiovascular functions.

Uses

Antipsychotic.

Definition

ChEBI: Fluphenazine enanthate is a member of phenothiazines.

in vivo

Fluphenazine enanthate (2,4, 8 mg/kg; IM) significant inhibition of the avoidance performance is observed as long as 16, 23, and 28 days, respectively[1].
Fluphenazine enanthate (8 mg/kg) drinking behavior is almost completely suppressed for 24 hours immediately following the administration[1].
Fluphenazine enanthate (8 mg/kg) produces transient body weight Iosses in the rats[1].

Animal Model:Fifty-four male adult rats of Wistar strain[1]
Dosage:2, 4, and 8 mg/kg
Administration:Index medicus (IM )
Result:Three doses of Fluphenazine enanthate significant inhibition of the avoidance performance was observed as long as 16, 23, and 28 days, respectively.

fluphenazine O-enantateSupplier

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