FUMARIC ACID-D4 Chemical Properties

Melting point:

299-300 °C (subl.)(lit.)

form 

solid

InChI

1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1+/i1D,2D/hD2

InChIKey

VZCYOOQTPOCHFL-JXRVJRKUSA-N

SMILES

[2H]OC(=O)\C([2H])=C(/[2H])C(=O)O[2H]

CAS Number Unlabeled

110-17-8

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2

MSDS

• Language:English Provider:SigmaAldrich

FUMARIC ACID-D4 Usage And Synthesis

Uses

Fumaric acid-d4 is the deuterium labeled Fumaric acid[1]. Fumaric acid, associated with fumarase deficiency, is identified as an oncometabolite or an endogenous, cancer causing metabolite[2].

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Whelan DT, et al. Fumaric aciduria: a new organic aciduria, associated with mental retardation and speech impairment. Clin Chim Acta. 1983 Aug 31;132(3):301-8. DOI:10.1016/0009-8981(83)90008-6

FUMARIC ACID-D4(194160-45-7)Related Product Information

• Fumaric acid
• FUMARIC-2,3-D2 ACID
• FUMARIC ACID-D4
• FUMARIC ACID-13C4,D4
• 2-BUTENE-2,3-D2 (GAS) (CIS/TRANS MIXTURE)