Tiazofurine Chemical Properties

Melting point:

145-146°

alpha 

D25 -9° (c = 0.5 in ethanol)

Density 

1.4797 (rough estimate)

refractive index 

1.6800 (estimate)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

solubility 

DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)

form 

Solid

color 

White to Pale Beige

Stability:

Very Very Hygroscopic

Tiazofurine Usage And Synthesis

Chemical Properties

White Solid

Uses

Tiazofurin has antitumor activity and is a potential therapeutic agent in the treatment of cancer. Tiazofurin acts as an inhibitor of Inosine-5''-monophosphate (IMP) dehydrogenase.

Definition

ChEBI: A C-glycosyl compound that is 1,3-thiazole-4-carboxamide in which the hydrogen at position 2 has been replaced by a beta-D-ribofuranosyl group. It is metabolised to thiazole-4-carboxamide adenine dinucle tide (TAD), a selective inhibitor of inosine monophosphate dehydrogenase (IMP dehydrogenase).

brand name

Tiazofurine is INN.

Tiazofurine(60084-10-8)Related Product Information

• Hydroxyethyl Cellulose
• Nitrofurazone
• TIAZOFURINE, [3H]-
• 1-(2-PROPYL-1,3-THIAZOL-4-YL)METHANAMINE
• (4-METHYLTHIAZOL-2-YL)METHANOL
• Tiazofurine
• thiazole-4-carboxamide adenine dinucleotide