DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2
DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 Basic information
- Product Name:
- DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2
- Synonyms:
-
- δ-Aminovaleryl-[Pro9, Leu(N-Me)10]-SubstanceP Fragment 7-11
- N-(5-Amino-1-oxopentyl)-L-Phe-L-Phe-L-Pro-N-methyl-L-Leu-L-Met-NH2
- (2S)-1-[(2S)-2-[[(2S)-2-(5-aminopentanoylamino)-3-phenyl-propanoyl]amino]-3-phenyl-propanoyl]-N-[(1S)-1-[[(1S)-1-carbamoyl-3-(methylthio)propyl]carbamoyl]-3-methyl-butyl]-N-methyl-pyrrolidine-2-carboxamide
- (2S)-N-[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(2S)-2-[[(2S)-2-(5-aminopentanoylamino)-3-phenylpropanoyl]amino]-3-phenylpropanoyl]-N-methylpyrrolidine-2-carboxamide
- (2S)-N-[(2S)-1-[[(2S)-1-azanyl-4-methylsulfanyl-1-oxo-butan-2-yl]amino]-4-methyl-1-oxo-pentan-2-yl]-1-[(2S)-2-[[(2S)-2-(5-azanylpentanoylamino)-3-phenyl-propanoyl]amino]-3-phenyl-propanoyl]-N-methyl-pyrrolidine-2-carboxamide
- d-AMinovaleryl-(Pro9,N-Me-Leu10)-Substance P (7-11)
- d-AMinovaleryl-Phe-Phe-Pro-N-Me-Leu-Met-NH2
- GR 73632
- CAS:
- 133156-06-6
- MF:
- C40H59N7O6S
- MW:
- 766
- Product Categories:
-
- AgonistPeptides for Cell Biology
- Neuropeptides
- Peptides for Cell Biology
- Tachykinins
- Mol File:
- 133156-06-6.mol
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DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 Chemical Properties
- Boiling point:
- 1082.2±65.0 °C(Predicted)
- Density
- 1.198±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Water:1.0(Max Conc. mg/mL);1.31(Max Conc. mM)
- pka
- 13.34±0.46(Predicted)
- form
- Powder
- color
- White to off-white
- Water Solubility
- Soluble to 1 mg/ml in water
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Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
MSDS
- Language:English Provider:SigmaAldrich
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DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 Usage And Synthesis
Uses
GR 73632 is a NK1 tachykinin receptor agonist used in the treatment of asthma and gastrointestinal disorders. It is involved in the contraction of muscles.
General Description
Neurokinin (NK) receptors are acted upon by tachykinins or neurokinins namely, NKA and NKB. These are endogenous ligands. An exogenous agonist/ligand for NK1 is GR 64349 petpide.
Biochem/physiol Actions
GR 73632 interacts with neurokinin (NK1) receptor, which results in rhythmic tapping of hind-foot in gerbils. Administration of this peptide in the intra-ventral tegmental area (VTA) results in locomotor activity. It interacts with and activates NK1 receptors present on smooth muscle and interstitial cells of Cajal, resulting in elevated distention-induced peristalsis.
storage
Store at -20°C
DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2Supplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
Amadis Chemical Company Limited
- Tel
- 571-89925085
- sales@amadischem.com
Nanjing Leon Biological Technology Co., Ltd.
- Tel
- 17705183659
- sales@njleonbiotech.com