Basic information Uses Safety Supplier Related

5'-O-(4,4'-DIMETHOXYTRITYL)-N6-PHENOXYACETYL-2'-DEOXYADENOSINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE

Basic information Uses Safety Supplier Related

5'-O-(4,4'-DIMETHOXYTRITYL)-N6-PHENOXYACETYL-2'-DEOXYADENOSINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE Basic information

Product Name:
5'-O-(4,4'-DIMETHOXYTRITYL)-N6-PHENOXYACETYL-2'-DEOXYADENOSINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE
Synonyms:
  • DMT-dA(tac) amidite
  • 5'-O-(4,4'-DIMETHOXYTRITYL)-N6-PHENOXYACETYL-2'-DEOXYADENOSINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE
  • 5''-O-(4,4''-Dimethoxytrityl)-N6-Phenoxyacetyl-2''-deoxyadenosine-3''-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
  • 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite
  • 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(phenoxyacetyl)-adenosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
  • Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(phenoxyacetyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
  • DMT-dA(PAc) Phosphoramidite
  • 5'-Dimethoxytrityl-N-phenoxyacetyl-2'-deoxyAdenosine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
CAS:
110543-74-3
MF:
C48H54N7O8P
MW:
887.96
EINECS:
2017-001-1
Product Categories:
  • DNA Amidites
  • Fast Deprotection DNA Amidites
  • Sigma-Proligo
  • Pharmaceutical
Mol File:
110543-74-3.mol
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5'-O-(4,4'-DIMETHOXYTRITYL)-N6-PHENOXYACETYL-2'-DEOXYADENOSINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE Chemical Properties

storage temp. 
Store at -20°C
solubility 
DMSO: Soluble: = 10 mg/ml
Ethanol: Sparingly soluble: 1-10 mg/ml
form 
Solid
pka
7.87±0.43(Predicted)
color 
White to off-white
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5'-O-(4,4'-DIMETHOXYTRITYL)-N6-PHENOXYACETYL-2'-DEOXYADENOSINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE Usage And Synthesis

Uses

2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite is a useful research chemical compound.

Uses

DMT-dA(PAc) Phosphoramidite is a dIPhosphoramidite and can be used for DNA or RNA synthesis.

References

[1] Keyhani S, et al. Chemo-Enzymatic Synthesis of Position-Specifically Modified RNA for Biophysical Studies including Light Control and NMR Spectroscopy. Angew Chem Int Ed Engl. 2018 Sep 10;57(37):12017-12021. DOI:10.1002/anie.201807125
[2] XIE Z, YANG Y, WANG Z, et al. Dithioethanol (DTE)-Conjugated Deoxyribose Cyclic Dinucleotide Prodrugs (DTE-dCDNs) as STING Agonist[J]. International Journal of Molecular Sciences, 2023, 53 17. DOI: 10.3390/ijms25010086

5'-O-(4,4'-DIMETHOXYTRITYL)-N6-PHENOXYACETYL-2'-DEOXYADENOSINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITESupplier

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5'-O-(4,4'-DIMETHOXYTRITYL)-N6-PHENOXYACETYL-2'-DEOXYADENOSINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE(110543-74-3)Related Product Information