Basic information Safety Supplier Related

GYKI 53405

Basic information Safety Supplier Related

GYKI 53405 Basic information

Product Name:
GYKI 53405
Synonyms:
  • GYKI 53405
  • LY 293606
  • 1-[5-(4-aminophenyl)-8-methyl-8,9-dihydro-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-7-yl]ethanone
  • Ethanone, 1-[5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-7-yl]-
CAS:
143691-37-6
MF:
C19H19N3O3
MW:
337.37
Mol File:
143691-37-6.mol
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GYKI 53405 Usage And Synthesis

Description

GYKI-53405, also known as LY 293606, is a noncompetitive AMPA receptor antagonist. GYKI-53405 binds specifically to Xenopus brain membranes with KD and Bmax values of 4.5 microM and 35 pmol mg-1 protein respectively. Binding is increased in the presence of Mg2+ and is unaffected by AMPA or kainate.

GYKI 53405Supplier

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