kadsurenone
kadsurenone Basic information
- Product Name:
- kadsurenone
- Synonyms:
-
- kadsurenone
- (2S)-2α-(3,4-Dimethoxyphenyl)-3,3a-dihydro-3aα-methoxy-3β-methyl-5-(2-propenyl)-6(2H)-benzofuranone
- 6(2H)-Benzofuranone, 2-(3,4-dimethoxyphenyl)-3,3A-dihydro-3A-methoxy-3-methyl-5-(2-propenyl)-, (2S-(2alpha,3beta,3aalpha))-
- (+)-Kadsurenone
- (2S,3R,3aS)-5-Allyl-2-(3,4-dimethoxyphenyl)-3a-methoxy-3-methyl-3,3a-dihydrobenzofuran-6(2H)-one
- CAS:
- 95851-37-9
- MF:
- C21H24O5
- MW:
- 356.416
- Mol File:
- 95851-37-9.mol
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kadsurenone Chemical Properties
- form
- Solid
- color
- White to off-white
- LogP
- 2.870 (est)
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kadsurenone Usage And Synthesis
Uses
Kadsurenone acts as a platelet activating factor (PAF) receptor antagonist. PAF is an important mediator of endotoxin-induced hypotension in rats.
Definition
ChEBI: Kadsurenone is a member of benzofurans.
in vivo
Kadsurenone (i.v.; 20 and 30 mg/kg) undergoes hepatobiliary excretion but might not be regulated by P-glycoprotein (P-gp) transported system[1].
| Animal Model: | Sprague-Dawley rats[1] |
| Dosage: | 0 and 30 mg/kg |
| Administration: | IV |
| Result: | Could go through hepatobiliary excretion. |
kadsurenoneSupplier
ChemStrong Scientific Co.,Ltd
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Chengdu Push Bio-Technology Co., Ltd.
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Shanghai Standard Technology Co.,Ltd.
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Energy Chemical
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Bide Pharmatech Ltd.
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- 400-1647117 13681763483
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