Bamaluzole Chemical Properties

storage temp. 

Store at -20°C

solubility 

Soluble in DMSO

Bamaluzole Usage And Synthesis

Originator

Bamaluzole,Onbio Inc.

Uses

Bamaluzole, is a GABA receptor agonist.

Manufacturing Process

1-Chlorophenyl-2-methanol is dissolved in dimethylformamide; NaH is added and the mixture is stirred at 20°C for 1 h. After a solution of 4-chloro-1- methyl-1H-imidazo[4,5-c]pyridine [melting point 132°-134°C; obtainable by reaction of 4-methylamino-3-nitropyridine with HCl/SnCl2 to give 3-amino-2- chloro-4-methylaminopyridine (melting point 170°-173°C) and reaction with HCOOH/acetic anhydride] in dimethylformamide has been added, the mixture is stirred at 90°-95°C for 15 h. The mixture is evaporated and the residue is worked up in the customary manner to give 4-o-chlorobenzyloxy-1-methyl- 1H-imidazo[4,5-c]pyridine, melting point 132°-135°C (crystallize from ethyl acetate-tetrahydofuran).

Therapeutic Function

Anticonvulsant

Bamaluzole(87034-87-5)Related Product Information

• Bamaluzole
• 3H-IMIDAZO[4,5-C]PYRIDINE
• 2-(BENZYLOXY)PYRIDINE
• 5-AZABENZIMIDAZOLE