(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride Chemical Properties

Melting point:

114-117°C

Density 

1.2g/cm3 at 20℃

vapor pressure 

0-0Pa at 20-25℃

storage temp. 

room temp

solubility 

Acetone (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly)

form 

solid

color 

white to off-white

Stability:

Hygroscopic

LogP

3.1 at 20℃ and pH7

Surface tension

72.3mN/m at 1g/L and 20℃

Safety Information

WGK Germany 

2

HS Code 

2934990002

(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride Usage And Synthesis

Chemical Properties

White to Off-White Solid

Uses

It is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease.

Biochem/physiol Actions

Rotigotine is a dopamine receptor agonist with preference for D3 receptors over D2 and D1. As such, it is an effective anti-Parkinsonian agent. Racemic rotigotine is about 50 times as potent as quinpirole, the gold standard D2 agonist.

storage

room temperature (desiccate)

(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride(125572-93-2)Related Product Information

• 1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-
• METHYL-(2-THIOPHEN-2-YL-ETHYL)-AMINE HYDROCHLORIDE
• (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
• Thiophene-2-ethylamine
• ROTIGOTINE
• 2-NAPHTHALENAMINE, 1,2,3,4-TETRAHYDRO-N-METHYL-N-PROPYL-, HYDROCHLORIDE