N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu
N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu Basic information
- Product Name:
- N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu
- Synonyms:
-
- N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu
- 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine
- 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(tert-butyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine
- 5'-DMT-2'-TBDMS-iBu-rG
- N-(9-((2R,3R,4R,5R)-5-((Bis(4-Methoxyphenyl)(phenyl)Methoxy)Methyl)-3-((tert-butyldiMethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyraMide
- 5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-[(1,1-diMethylethyl)diMethylsilyl]-N-(2-Methyl-1-oxopropyl)-Guanosine
- 5'-O-DMT-N-isobutyryl-2'-O-TBDMS-guanosine
- 5-O-(4,4-Dimethoxytrityl)-2-O-(tertbutyldimethylsilyl)-N-isobutyryl-Guanosine
- CAS:
- 81279-39-2
- MF:
- C41H51N5O8Si
- MW:
- 769.96
- EINECS:
- 2017-001-1
- Mol File:
- 81279-39-2.mol
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N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu Chemical Properties
- Density
- 1.25
- storage temp.
- 2-8°C
- pka
- 9.16±0.20(Predicted)
- form
- Solid
- color
- White to light yellow
- InChIKey
- JMCNKJFOIJGYRG-HVXBIEPNNA-N
- SMILES
- O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](O[Si](C(C)(C)C)(C)C)[C@@H]1O |&1:25,27,44,53,r|
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N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu Usage And Synthesis
Uses
5''-O-DMT-2''-O-iBu-N-Bz-Guanosine (cas# 81279-39-2) is a nucleotide used in the preparation of 4''-C-methoxy-2''-deoxy-2''-fluoro modified ribonucleotides to improve metabolic stability and elicit efficient RNAi-mediated gene silencing.
N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-guSupplier
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