Basic information Safety Supplier Related

N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu

Basic information Safety Supplier Related

N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu Basic information

Product Name:
N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu
Synonyms:
  • N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu
  • 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine
  • 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(tert-butyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine
  • 5'-DMT-2'-TBDMS-iBu-rG
  • N-(9-((2R,3R,4R,5R)-5-((Bis(4-Methoxyphenyl)(phenyl)Methoxy)Methyl)-3-((tert-butyldiMethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyraMide
  • 5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-[(1,1-diMethylethyl)diMethylsilyl]-N-(2-Methyl-1-oxopropyl)-Guanosine
  • 5'-O-DMT-N-isobutyryl-2'-O-TBDMS-guanosine
  • 5-O-(4,4-Dimethoxytrityl)-2-O-(tertbutyldimethylsilyl)-N-isobutyryl-Guanosine
CAS:
81279-39-2
MF:
C41H51N5O8Si
MW:
769.96
EINECS:
2017-001-1
Mol File:
81279-39-2.mol
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N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu Chemical Properties

Density 
1.25
storage temp. 
2-8°C
pka
9.16±0.20(Predicted)
form 
Solid
color 
White to light yellow
InChIKey
JMCNKJFOIJGYRG-HVXBIEPNNA-N
SMILES
O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](O[Si](C(C)(C)C)(C)C)[C@@H]1O |&1:25,27,44,53,r|
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N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu Usage And Synthesis

Uses

5''-O-DMT-2''-O-iBu-N-Bz-Guanosine (cas# 81279-39-2) is a nucleotide used in the preparation of 4''-C-methoxy-2''-deoxy-2''-fluoro modified ribonucleotides to improve metabolic stability and elicit efficient RNAi-mediated gene silencing.

N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-guSupplier

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