2-(4-BROMOPHENYL)-6-CHLOROQUINOLINE-4-CARBOXYLICACID
2-(4-BROMOPHENYL)-6-CHLOROQUINOLINE-4-CARBOXYLICACID Basic information
- Product Name:
- 2-(4-BROMOPHENYL)-6-CHLOROQUINOLINE-4-CARBOXYLICACID
- Synonyms:
-
- 2-(4-bromophenyl)-6-chloro-4-quinolinecarboxylic acid
- 2-(4-bromophenyl)-6-chloro-cinchoninic acid
- 4-Quinolinecarboxylic acid, 2-(4-bromophenyl)-6-chloro-
- A2497/0106210
- 2-(4-BROMOPHENYL)-6-CHLOROQUINOLINE-4-CARBOXYLICACID
- AIDS228061
- AIDS-228061
- EU-0042456
- CAS:
- 342017-94-1
- MF:
- C16H9BrClNO2
- MW:
- 362.61
- Mol File:
- 342017-94-1.mol
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Safety Information
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
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2-(4-BROMOPHENYL)-6-CHLOROQUINOLINE-4-CARBOXYLICACID Usage And Synthesis
Uses
Aminoacyl tRNA synthetase-IN-4 (Compound 1l) is an inhibitor of Aminoacyl tRNA synthetase, with an IC50 of 0.026 μM for C.albicans prolyl-tRNA synthetase. Aminoacyl tRNA synthetase-IN-4 can be used for antifungal research[1].
References
[1] Yu XY, et al. A series of quinoline analogues as potent inhibitors of C. albicans prolyl tRNA synthetase. Bioorg Med Chem Lett. 2001 Feb 26;11(4):541-4. DOI:10.1016/s0960-894x(00)00697-1
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