Basic information Safety Supplier Related

2-(4,5-DIHYDROIMIDAZOL-2-YL)QUINOLINE HYDROCHLORIDE

Basic information Safety Supplier Related

2-(4,5-DIHYDROIMIDAZOL-2-YL)QUINOLINE HYDROCHLORIDE Basic information

Product Name:
2-(4,5-DIHYDROIMIDAZOL-2-YL)QUINOLINE HYDROCHLORIDE
Synonyms:
  • BU 224 HYDROCHLORIDE
  • 2-(4,5-DIHYDROIMIDAZOL-2-YL)QUINOLINE HYDROCHLORIDE
  • Quinoline, 2-(4,5-dihydro-1H-imidazol-2-yl)-
CAS:
187173-05-3
MF:
C12H11N3
MW:
197.24
Mol File:
187173-05-3.mol
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2-(4,5-DIHYDROIMIDAZOL-2-YL)QUINOLINE HYDROCHLORIDE Chemical Properties

Boiling point:
372.9±34.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
Desiccate at RT
solubility 
ethanol: 1.2 mg/mL
form 
solid
pka
9.87±0.40(Predicted)
color 
white
InChI
1S/C12H11N3.ClH/c1-2-4-10-9(3-1)5-6-11(15-10)12-13-7-8-14-12;/h1-6H,7-8H2,(H,13,14);1H
InChIKey
DDFHQXAQWZWRSQ-UHFFFAOYSA-N
SMILES
Cl[H].C1CN=C(N1)c2ccc3ccccc3n2
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

MSDS

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2-(4,5-DIHYDROIMIDAZOL-2-YL)QUINOLINE HYDROCHLORIDE Usage And Synthesis

Uses

BU224 is one of the two most widely studied I2 receptor ligands and have antinociceptive and antidepressant-?like activities in rodents.

Biological Activity

High affinity ligand for the imidazoline I 2 binding site (K i = 2.1 nM). Putative I 2 antagonist; antagonizes the effects of imidazoline ligands on morphine antinociception. Produces ipsiversive rotational behavior in rats with a full 6-OHDA lesion of the nigrostriatal tract.

2-(4,5-DIHYDROIMIDAZOL-2-YL)QUINOLINE HYDROCHLORIDESupplier

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