(S)-2,3-DIMETHOXY-5-[3-[[(4-METHYLPHENYL)-SULFONYL]OXY]-PROPYL]-N-[[1-(2-PROPENYL)-2-PYRROLIDINYL]METHYL]-BENZAMIDE Chemical Properties

Boiling point:

632.8±55.0 °C(Predicted)

Density 

1.171±0.06 g/cm3(Predicted)

pka

14.15±0.46(Predicted)

form 

Oil

color 

Light yellow to yellow

(S)-2,3-DIMETHOXY-5-[3-[[(4-METHYLPHENYL)-SULFONYL]OXY]-PROPYL]-N-[[1-(2-PROPENYL)-2-PYRROLIDINYL]METHYL]-BENZAMIDE Usage And Synthesis

Chemical Properties

Colourless to yellowish oil

Uses

Fallypride precursor (Compound 15) can be used for synthesis of Fallypride (HY-135497). Fallypride is an antagonist of the dopamine D2/D3 receptor. Fallypride can be used as a positron emission tomography (PET) radiotracer when labeled with 18F[1].

References

[1] Mukherjee J, et al., Fluorinated benzamide neuroleptics--III. Development of (S)-N-[(1-allyl-2-pyrrolidinyl)methyl]-5-(3-[18F]fluoropropyl)-2, 3-dimethoxybenzamide as an improved dopamine D-2 receptor tracer. Nucl Med Biol. 1995 Apr;22(3):283-96. DOI:10.1016/0969-8051(94)00117-3

(S)-2,3-DIMETHOXY-5-[3-[[(4-METHYLPHENYL)-SULFONYL]OXY]-PROPYL]-N-[[1-(2-PROPENYL)-2-PYRROLIDINYL]METHYL]-BENZAMIDE(166173-74-6)Related Product Information

• (S)-2,3-DIMETHOXY-5-[3-[[(4-METHYLPHENYL)-SULFONYL]OXY]-PROPYL]-N-[[1-(2-PROPENYL)-2-PYRROLIDINYL]METHYL]-BENZAMIDE
• 1-Allyl-2-aminomethylpyrrolidine
• BENZAMIDE, 2-METHOXY-5-[3-[[(4-METHYLPHENYL)SULFONYL]OXY]PROPYL]-N-[[1-(2-PROPENYL)-2-PYRROLIDINYL]METHYL]-
• (R)-2-Methylpyrrolidine tosylate