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Niranthin

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Niranthin Basic information

Product Name:
Niranthin
Synonyms:
  • Niranthin
  • 4-Methylenedioxylignan
  • 9'-PentaMethoxy-3
  • 3',4',5,9,9'-PentaMethoxy-3,4-Methylenedioxylignan
  • rac-Niranthin
  • Pearlgrass
  • 1,3-Benzodioxole,6-[(2R,3R)-4-(3,4-dimethoxyphenyl)-2,3-bis(methoxymethyl)butyl]-4-methoxy-,rel-
  • 6-[(2R,3R)-3-[(3,4-dimethoxyphenyl)methyl]-4-methoxy-2-(methoxymethyl)butyl]-4-methoxy-1,3-benzodioxole
CAS:
50656-77-4
MF:
C24H32O7
MW:
432.51
Mol File:
50656-77-4.mol
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Niranthin Chemical Properties

Boiling point:
559.5±50.0 °C(Predicted)
Density 
1.142±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 15 mg/ml,DMSO: 10 mg/ml,Ethanol: 5 mg/ml
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Niranthin Usage And Synthesis

Uses

rac-Niranthin is a lignan compound isolated from the plant Phyllanthus amarus and shows anti-leishmanial activity. It acts through induction of topoisomerase I-mediated DNA-protein adduct formation in Leishmania cells triggering apoptosis of cellular nucleases. It also maintains the ability to reduce uric acid concentrations through xanthine oxidase inhibition.

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