H-TRP-TRP-GLY-LYS-LYS-TYR-ARG-ALA-SER-LYS-LEU-GLY-LEU-ALA-ARG-OH
H-TRP-TRP-GLY-LYS-LYS-TYR-ARG-ALA-SER-LYS-LEU-GLY-LEU-ALA-ARG-OH Basic information
- Product Name:
- H-TRP-TRP-GLY-LYS-LYS-TYR-ARG-ALA-SER-LYS-LEU-GLY-LEU-ALA-ARG-OH
- Synonyms:
-
- [TRP63,64]-C3A (63-77)
- (TRP63,TRP64)-C3A (63-77)
- TRP-TRP-GLY-LYS-LYS-TYR-ARG-ALA-SER-LYS-LEU-GLY-LEU-ALA-ARG
- WWGKKYRASKLGLAR
- H-TRP-TRP-GLY-LYS-LYS-TYR-ARG-ALA-SER-LYS-LEU-GLY-LEU-ALA-ARG-OH
- Complement C3a receptor agonist peptide EP141
- L-Arginine, L-tryptophyl-L-tryptophylglycyl-L-lysyl-L-lysyl-L-tyrosyl-L-arginyl-L-alanyl-L-seryl-L-lysyl-L-leucylglycyl-L-leucyl-L-alanyl-
- (Trp??,Trp??)-C3a (63-77)
- CAS:
- 130154-64-2
- MF:
- C86H134N26O18
- MW:
- 1820.15
- Product Categories:
-
- peptide
- Mol File:
- 130154-64-2.mol
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H-TRP-TRP-GLY-LYS-LYS-TYR-ARG-ALA-SER-LYS-LEU-GLY-LEU-ALA-ARG-OH Chemical Properties
- Density
- 1.43±0.1 g/cm3(Predicted)
- storage temp.
- -15°C
- pka
- 3.34±0.10(Predicted)
- Sequence
- Trp-Trp-Gly-Lys-Lys-Tyr-Arg-Ala-Ser-Lys-Leu-Gly-Leu-Ala-Arg
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H-TRP-TRP-GLY-LYS-LYS-TYR-ARG-ALA-SER-LYS-LEU-GLY-LEU-ALA-ARG-OH Usage And Synthesis
Chemical Properties
White powder
Uses
(Trp63,Trp64)?-?C3a(63-77) is a C3a synthetic analogue peptide, which exhibits Ca2+ stimulating efficacy in human neutrophils and hC3aR or mC3aR expressing RBL-2H3 cells with EC50 of 9.5, 2.0 and 0.8 nM, respectively[1].
References
[1] Ames RS, et al., Evidence that the receptor for C4a is distinct from the C3a receptor. Immunopharmacology. 1997 Dec;38(1-2):87-92. DOI:10.1016/s0162-3109(97)00079-9
H-TRP-TRP-GLY-LYS-LYS-TYR-ARG-ALA-SER-LYS-LEU-GLY-LEU-ALA-ARG-OHSupplier
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