(+/-)-LY367385
(+/-)-LY367385 Basic information
- Product Name:
- (+/-)-LY367385
- Synonyms:
-
- 4-(AMINO-CARBOXY-METHYL)-3-METHYL-BENZOIC ACID
- BENZENEACETIC ACID, A-AMINO-4-CARBOXY-2-METHYL-
- LY 367385, (±)-
- Benzeneacetic acid, α-amino-4-carboxy-2-methyl-
- (+/-)-LY367385
- CAS:
- 198419-90-8
- MF:
- C10H11NO4
- MW:
- 209.2
- Mol File:
- 198419-90-8.mol
More
Less
(+/-)-LY367385 Chemical Properties
- Boiling point:
- 434.0±45.0 °C(Predicted)
- Density
- 1.393±0.06 g/cm3(Predicted)
- solubility
- Water: 20 mg/ml
- form
- A solid
- pka
- 1.72±0.10(Predicted)
- color
- White to off-white
More
Less
(+/-)-LY367385 Usage And Synthesis
Description
(±)-LY367385 is an antagonist of metabotropic glutamate receptor 1α (mGluR1α).1 It inhibits phosphoinositide (PI) hydrolysis selectively in AV-12 cells expressing mGluR1α over those expressing mGluR5a (IC50s = 19 and >300 μM, respectively).
References
1. Salt, T.E., Jones, H.E., Copeland, C.S., et al. Function of mGlu1 receptors in the modulation of nociceptive processing in the thalamus Neuropharmacology 79(100),405-411(2014).
(+/-)-LY367385Supplier
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
BOC Sciences
- Tel
- info@bocsci.com
Changzhou Furuisi Biotechnology Co., Ltd
- Tel
- 0519-85524369
- 3477467573@qq.com
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
ChemeGen 中国
- Tel
- 18818260767
- 2625930290@qq.com