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ChemicalBook >  Product Catalog >  Biologics >  Biochemical Reagents >  Antagonist >  4-DIMETHYLAMINO-7-(4-ETHYL-PHENYL)-7H-9-THIA-1,5,7-TRIAZA-FLUOREN-8-ONE

4-DIMETHYLAMINO-7-(4-ETHYL-PHENYL)-7H-9-THIA-1,5,7-TRIAZA-FLUOREN-8-ONE

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4-DIMETHYLAMINO-7-(4-ETHYL-PHENYL)-7H-9-THIA-1,5,7-TRIAZA-FLUOREN-8-ONE Basic information

Product Name:
4-DIMETHYLAMINO-7-(4-ETHYL-PHENYL)-7H-9-THIA-1,5,7-TRIAZA-FLUOREN-8-ONE
Synonyms:
  • 4-DIMETHYLAMINO-7-(4-ETHYL-PHENYL)-7H-9-THIA-1,5,7-TRIAZA-FLUOREN-8-ONE
  • Pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one, 9-(dimethylamino)-3-(4-ethylphenyl)-
  • A-794282
  • A 794282,A794282
  • 9-(Dimethylamino)-3-(4-ethylphenyl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one
CAS:
869802-44-8
MF:
C19H18N4OS
MW:
350.44
Mol File:
869802-44-8.mol
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4-DIMETHYLAMINO-7-(4-ETHYL-PHENYL)-7H-9-THIA-1,5,7-TRIAZA-FLUOREN-8-ONE Usage And Synthesis

Description

A-794282 is a selective mGluR1 antagonist.

Uses

A-794282 is a compound with analgesic activity and is a selective mGlu1 receptor antagonist that significantly reduces pain behaviors in a postoperative pain model, but motor side effects may occur at higher doses.

IC 50

mGluR1

References

[1] Analgesic activity of metabotropic glutamate receptor 1 antagonists on spontaneous post-operative pain in rats DOI:10.1016/j.ejphar.2007.09.047
[2] [Research progress of selective mGluR1 antagonists] PMID:22242445

4-DIMETHYLAMINO-7-(4-ETHYL-PHENYL)-7H-9-THIA-1,5,7-TRIAZA-FLUOREN-8-ONESupplier

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