4-[(3AR,4S,9BS)-6-ETHOXY-3A,4,5,9B-TETRAHYDRO-3H-CYCLOPENTA[C]QUINOLIN-4-YL]BENZOIC ACID
4-[(3AR,4S,9BS)-6-ETHOXY-3A,4,5,9B-TETRAHYDRO-3H-CYCLOPENTA[C]QUINOLIN-4-YL]BENZOIC ACID Basic information
- Product Name:
- 4-[(3AR,4S,9BS)-6-ETHOXY-3A,4,5,9B-TETRAHYDRO-3H-CYCLOPENTA[C]QUINOLIN-4-YL]BENZOIC ACID
- Synonyms:
-
- 4-[(3AR,4S,9BS)-6-ETHOXY-3A,4,5,9B-TETRAHYDRO-3H-CYCLOPENTA[C]QUINOLIN-4-YL]BENZOIC ACID
- LIN28 inhibitor LI71 enantiomer
- 4-[(3aS,4R,9bR)-6-Ethoxy-3H,3aH,4H,5H,9bH-cyclopenta[c]quinolin-4-yl]benzoic acid
- Compound T41114(SC)
- CAS:
- 956189-58-5
- MF:
- C21H21NO3
- MW:
- 335.4
- Mol File:
- Mol File
More
Less
4-[(3AR,4S,9BS)-6-ETHOXY-3A,4,5,9B-TETRAHYDRO-3H-CYCLOPENTA[C]QUINOLIN-4-YL]BENZOIC ACID Chemical Properties
- form
- Solid
- color
- White to yellow
More
Less
4-[(3AR,4S,9BS)-6-ETHOXY-3A,4,5,9B-TETRAHYDRO-3H-CYCLOPENTA[C]QUINOLIN-4-YL]BENZOIC ACID Usage And Synthesis
Uses
LIN28 inhibitor LI71 enantiomer is the enantiomer of LIN28 inhibitor LI71 with less active. LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM[1].
References
[1] Wang L, et al. Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28. Cell Rep. 2018;23(10):3091-3101. DOI:10.1016/j.celrep.2018.04.116
4-[(3AR,4S,9BS)-6-ETHOXY-3A,4,5,9B-TETRAHYDRO-3H-CYCLOPENTA[C]QUINOLIN-4-YL]BENZOIC ACIDSupplier
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
TargetMol Chemicals Inc.
- Tel
- 4008200310
- marketing@tsbiochem.com
Shanghai Yifei Biotechnology Co. , Ltd.
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com
Nantong Hanfang Biotechnology Co. , Ltd.
- Tel
- hanfangpharma@126.com; 18616537568
- hanfangpharma@126.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354;
- support@targetmol.com