Basic information Safety Supplier Related

2'-Deoxy-5-[(triMethylsilyl)ethynyl]uridine 3',5'-Dibenzoate

Basic information Safety Supplier Related

2'-Deoxy-5-[(triMethylsilyl)ethynyl]uridine 3',5'-Dibenzoate Basic information

Product Name:
2'-Deoxy-5-[(triMethylsilyl)ethynyl]uridine 3',5'-Dibenzoate
Synonyms:
  • 2'-Deoxy-5-[(triMethylsilyl)ethynyl]uridine 3',5'-Dibenzoate
  • Uridine, 2'-deoxy-5-[(trimethylsilyl)ethynyl]-, 3',5'-dibenzoate (9CI)
  • ((2r,3s,5r)-3-(Benzoyloxy)-5-(2,4-dioxo-5-((trimethylsilyl)ethynyl)-3,4-dihydropyrimidin-1(2h)-yl)tetrahydrofuran-2-yl)methyl benzoate
CAS:
140424-82-4
MF:
C28H28N2O7Si
MW:
532.62
Product Categories:
  • Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
140424-82-4.mol
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2'-Deoxy-5-[(triMethylsilyl)ethynyl]uridine 3',5'-Dibenzoate Chemical Properties

Density 
1.31±0.1 g/cm3(Predicted)
pka
8.83±0.10(Predicted)
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2'-Deoxy-5-[(triMethylsilyl)ethynyl]uridine 3',5'-Dibenzoate Usage And Synthesis

Uses

2'-?Deoxy-?5-?[(trimethylsilyl)?ethynyl]?uridine 3’,5’-Dibenzoate is an protected intermediate in the synthesis of 5-Ethyl-2’-deoxyuridine (E915020), a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil (F596000), a potent antineoplastic agent in clinical use.

2'-Deoxy-5-[(triMethylsilyl)ethynyl]uridine 3',5'-DibenzoateSupplier

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