3-THIOPHEN-2-YL-BENZALDEHYDE Chemical Properties

Melting point:

65-69 °C (lit.)

Boiling point:

324.9±25.0 °C(Predicted)

Density 

1?+-.0.06 g/cm3(Predicted)

form 

solid

CAS DataBase Reference

107834-03-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

22

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

2934999090

MSDS

• Language:English Provider:SigmaAldrich

3-THIOPHEN-2-YL-BENZALDEHYDE Usage And Synthesis

Uses

4-(Thiophen-2-yl)benzaldehyde is a useful component in the synthesis of stimulus-?responsive luminescent organic materials via reactive an inkjet printing system.

Synthesis

To 2-bromothiophene (0.489 g, 3 mmol) and 4-formylphenylboronic acid (0.60 g, 4 mmol), K2CO3 (0.696 g, 1 N) and N,N-dimethylformamide (20 mL) were added in a 100 mL three-neck flask. After stirring and mixing under N2 protection for 30 min, tetrakis(triphenylphosphine)palladium (0.115 g, 0.1 mmol) was added. The reaction mixture was stirred at 90 °C for 6 hours. After completion of the reaction, it was naturally cooled to room temperature and the crude product was dissolved in dichloromethane and washed with 100 mL of water. The organic layer was dried with anhydrous MgSO4 to remove water. The final product was purified by recrystallization from ethyl acetate to give 0.46 g of yellow solid in 89% yield.

References

[1] Patent: CN108586438, 2018, A. Location in patent: Paragraph 0040; 0056-0058; 0062
[2] Molecules, 2017, vol. 22, # 3,
[3] Organic Letters, 2017, vol. 19, # 7, p. 1610 - 1613
[4] Patent: KR2017/124005, 2017, A. Location in patent: Paragraph 0206

3-THIOPHEN-2-YL-BENZALDEHYDE(107834-03-7)Related Product Information

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