9-KODE
9-KODE Basic information
- Product Name:
- 9-KODE
- Synonyms:
-
- 9-KODE
- 9-OXO-10(E),12(Z)-OCTADECADIENOIC ACID
- 9-OXOODE
- LUZSWWYKKLTDHU-ZJHFMPGASA-N
- 10,12-Octadecadienoic acid, 9-oxo-, (10E,12Z)-
- 9-OxoODE (9-KODE)
- 9-OxoODE(solution in ethanol)
- CAS:
- 54232-59-6
- MF:
- C18H30O3
- MW:
- 294.43
- Mol File:
- 54232-59-6.mol
9-KODE Chemical Properties
- Melting point:
- 49.5-51.5 °C
- Boiling point:
- 449.2±28.0 °C(Predicted)
- Density
- 0.966±0.06 g/cm3(Predicted)
- solubility
- DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
- pka
- 4.77±0.10(Predicted)
9-KODE Usage And Synthesis
Uses
9-OxoODE results from oxidation of the allylic hydroxyl of either 9(S)- or 9(R)-HODE. Rabbit reticulocyte plasma and mitochondrial membranes contain both 9- and 13-oxoODEs, representing about 2% of the total linoleate residues in the membranes. Most of these oxidized linoleate residues are esterified to membrane lipids.
Definition
ChEBI: 9-oxo-ODE is an oxooctadecadienoic acid that consists of (10E,12Z)-octadecadienoic acid with the oxo substituent located at position 9. It has a role as a metabolite. It is an oxooctadecadienoic acid and an enone. It is functionally related to a 9-HODE. It is a conjugate acid of a 9-oxo-ODE(1-).
References
[1] Kühn, et al. Occurrence of 9- and 13-keto-octadecadienoic acid in biological membranes oxygenated by the reticulocyte lipoxygenase. Arch. Biochem. Biophys. 279, 218-224 (1990).
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