Basic information Safety Supplier Related

Sorafenib Impurity 6

Basic information Safety Supplier Related

Sorafenib Impurity 6 Basic information

Product Name:
Sorafenib Impurity 6
Synonyms:
  • Sorafenib impurity Y
  • N-methyl-4-(4-(3-(3-(trifluoromethyl)
  • Sorafenib impurity 2/Deschloro Sorafenib/N-Methyl-4-[4-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxamide
  • Sorafenib Deschloro Impurity
  • N-methyl-4-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenoxy)picolinamide
  • 2-Pyridinecarboxamide, N-methyl-4-[4-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-
  • 4-[4-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methylpyridine-2-carboxamide
  • Deschloro Sorafenib
CAS:
1285533-84-7
MF:
C21H17F3N4O3
MW:
430.38
Mol File:
1285533-84-7.mol
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Sorafenib Impurity 6 Chemical Properties

Melting point:
187.6 °C
Boiling point:
498.1±45.0 °C(Predicted)
Density 
1.399±0.06 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
13.39±0.70(Predicted)
color 
Off-White to Light Brown
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Sorafenib Impurity 6 Usage And Synthesis

Uses

N-Methyl-4-[4-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxamide is an impurity of Sorafenib (S676850); a multiple kinase inhibitor targeting both RAF and receptor tyrosine kinases that promote angiogenesis. Also antineoplastic.

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