Acetyl-Tau Peptide (273-284) amide Chemical Properties

Boiling point:

1733.8±65.0 °C(Predicted)

Density 

1.204±0.06 g/cm3(Predicted)

pka

4.20±0.10(Predicted)

Sequence

Ac-Gly-Lys-Val-Gln-Ile-Ile-Asn-Lys-Lys-Leu-Asp-Leu-NH2

Acetyl-Tau Peptide (273-284) amide Usage And Synthesis

Uses

Acetyl-Tau Peptide (273-284) amide is an acetylated Tau peptide fragment. Acetyl-Tau Peptide (273-284) amide limits the substantial aggregation of Ac-Aβ(25–35)-NH2 and can be used as an inhibitor of Ac-Aβ(25–35)-NH2. Acetyl-Tau Peptide (273-284) amide can be used as an experimental model to investigate the Aβ/Tau cross-interaction [1][2].

References

[1] Di Natale G, et al. Aβ and Tau Interact with Metal Ions, Lipid Membranes and Peptide-Based Amyloid Inhibitors: Are These Common Features Relevant in Alzheimer's Disease? Molecules. 2022 Aug 9;27(16):5066. DOI:10.3390/molecules27165066
[2] Do TD, et al. Interactions between amyloid-β and Tau fragments promote aberrant aggregates: implications for amyloid toxicity. J Phys Chem B. 2014 Sep 25;118(38):11220-30. DOI:10.1021/jp506258g

Acetyl-Tau Peptide (273-284) amide(1684399-52-7)Related Product Information

• Tau Peptide (323-335)
• Tau Peptide (306-317)
• Tau Peptide (273-284)
• Tau Peptide (337-368) (Repeat 4 Domain)
• Tau Peptide (277-291)
• Tau Peptide (306-336) (Repeat 3 Domain)
• Tau Peptide (301-315)
• Tau Peptide (307-321)
• Tau Peptide (275-305) (Repeat 2 Domain)
• Biotinyl-Tau Peptide (306-336) (Repeat 3 Domain)
• Tau Peptide (298-312)
• Tau Peptide (274-288)
• Tau Peptide (304-318)
• Tau Peptide (379-408)
• Tau Peptide (295-309)