JNJ7925476 HCl
JNJ7925476 HCl Basic information
- Product Name:
- JNJ7925476 HCl
- Synonyms:
-
- JNJ7925476 HCl
- JNJ 7925476
- JNJ7925476
- JNJ-7925476
- JNJ7925476 HCl,JNJ 7925476 HCl
- CAS:
- 109085-56-5
- MF:
- C20H20ClN
- MW:
- 309.8325
- Mol File:
- 109085-56-5.mol
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JNJ7925476 HCl Usage And Synthesis
Uses
JNJ-7925476 (hydrochloride) is a triple monoamine uptake inhibitor with the ability to regulate neurotransmitter levels and antidepressant activity. JNJ-7925476 (hydrochloride) can be rapidly absorbed into the plasma in rats, with a higher concentration in the brain than in plasma. It can induce an increase in the levels of extracellular serotonin, dopamine, and norepinephrine in the rat cerebral cortex, and exhibits antidepressant activity in the mouse tail suspension test.
References
[1] In-vitro and in-vivo characterization of JNJ-7925476, a novel triple monoamine uptake inhibitor