Basic information Safety Supplier Related

SODIUM 2-(4-METHOXYPHENOXY)PROPIONATE

Basic information Safety Supplier Related

SODIUM 2-(4-METHOXYPHENOXY)PROPIONATE Basic information

Product Name:
SODIUM 2-(4-METHOXYPHENOXY)PROPIONATE
Synonyms:
  • FEMA 3773
  • SODIUM 2-(4-METHOXYPHENOXY)PROPIONATE
  • Propanoic acid, 2-(4-methoxyphenoxy)-
  • SODIUM2-(4-METHOXYPHENOXY)PROPANOATE
  • 2-(4-METHOXYPHENOXY)PROPIONIC ACID SODIUM SALT
  • Lactisol
  • Sweetness inhibitor
  • Sweetness
CAS:
13794-15-5
MF:
C10H12O4
MW:
196.2
EINECS:
604-052-0
Mol File:
13794-15-5.mol
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SODIUM 2-(4-METHOXYPHENOXY)PROPIONATE Chemical Properties

Melting point:
92-94℃
Boiling point:
173-175 °C(Press: 1 Torr)
Density 
1.185
FEMA 
3773 | SODIUM 2-(4-METHOXYPHENOXY)PROPANOATE
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
3.29±0.10(Predicted)
color 
Pale Brown to Brown
JECFA Number
1029
LogP
1.650 (est)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
2918999090
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SODIUM 2-(4-METHOXYPHENOXY)PROPIONATE Usage And Synthesis

Chemical Properties

2-(4-Methoxyphenoxy)propanoate is a potent inhibitor of the sweetness of sucrose and other sweeteners.

Chemical Properties

Lactisole, the sodium salt of racemic 2(4 methoxyphenoxy) propionic acid, is a sweet-taste inhibitor marketed by Domino Sugar. It was affirmed as a GRAS flavor (FEMA no. 3773). At a concentration of 100–150 ppm, lactisole eliminates the sweet taste of a 10% sugar solution. This inhibition appears to be receptor related because lactisole also inhibits the sweet taste of aspartame. The (S?) enantiomer [CAS: 4276-74-8] (38), isolated from roasted coffee beans, is the active isomer; the (R+) enantiomer is inert.

Occurrence

Reported found in coffee beans.

Uses

Sodium 2-(4-methoxyphenoxy)propanoic acid is a taste modulator that inhibits the perception of sweetness in humans, but not in rats.

Definition

ChEBI: (S)-2-(4-Methoxyphenoxy)propanoic acid is a carboxylic acid and an aromatic ether.

Biochem/physiol Actions

As a taste modulator, the sodium salt inhibits the perception of sweetness in humans, but not in rats.

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