Basic information Safety Supplier Related

8-CHLOROGUANOSINE

Basic information Safety Supplier Related

8-CHLOROGUANOSINE Basic information

Product Name:
8-CHLOROGUANOSINE
Synonyms:
  • 8-CHLOROGUANOSINE
  • 8-CL-GUO
  • 8-Chloroguanoside
  • 8-Chloro-D-guanosine
  • GUANOSINE, 8-CHLORO-
  • 2-Amino-8-chloro-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one
CAS:
2104-68-9
MF:
C10H12ClN5O5
MW:
317.69
Mol File:
2104-68-9.mol
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8-CHLOROGUANOSINE Chemical Properties

Density 
2.35±0.1 g/cm3(Predicted)
pka
8.41±0.20(Predicted)
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8-CHLOROGUANOSINE Usage And Synthesis

Uses

8-Chloroguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

8-CHLOROGUANOSINESupplier

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