BRASSININ
BRASSININ Basic information
- Product Name:
- BRASSININ
- Synonyms:
-
- 1H-(INDOL-3-YLMETHYL)-DITHIOCARBAMIC ACID, METHYL ESTER
- BRASSININ
- methyl ((1H-indol-3-yl)methyl)carbamodithioate
- [(1H-Indole-3-yl)methyl]dithiocarbamic acid methyl ester
- 1H-Indole-3-ylmethyldithiocarbamic acid methyl ester
- Brassinine
- N-[(1H-Indol-3-yl)methyl]dithiocarbamic acid methyl ester
- N-(1H-Indol-3-ylMethyl)carbaModithioic Acid
- CAS:
- 105748-59-2
- MF:
- C11H12N2S2
- MW:
- 236.36
- Product Categories:
-
- Aromatics Compounds
- Aromatics
- Indole Derivatives
- Sulfur & Selenium Compounds
- Mol File:
- 105748-59-2.mol
BRASSININ Chemical Properties
- Melting point:
- 142-144°C
- storage temp.
- -20°C Freezer, Under Inert Atmosphere
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
- form
- Solid
- color
- Off-White to Pale Yellow
BRASSININ Usage And Synthesis
Chemical Properties
Off-White to Pale Yellow Solid
Uses
Brassinin is a plant metabolite of great significance due to its dual role both as an effective phytoalexin and as an early biosynthetic precursor of the majority of the phytoalexins produced by plants of the family Brassicaceae (Cruciferae).
Uses
A biosynthetic precursor of Brassilexin
Definition
ChEBI: Brassinin is a dithiocarbamic ester and an indole phytoalexin.
Biological Activity
Brassinin is a phytoalexin isolated from cruciferous vegetables th at exhibits anticancer, chemopreventive, antiproliferative and antifungal activities. In lung cancer cells, brassinin inhibits constitutive and IL-6-inducible STAT3 signaling through modulation of PIAS-3 and SOCS-3. It appears th at brassinin induces apoptosis in PC-3 prostate cancer cells via the suppression of PI3K/Akt/mTOR/S6K1 signaling.
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