AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-OH
AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-OH Basic information
- Product Name:
- AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-OH
- Synonyms:
-
- MBP (1-11), MOUSE
- AC-ASQKRPSQRSK
- AC-ASQKRPSQRSK-OH
- AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-OH
- ACETYL-MYELIN BASIC PROTEIN (MOUSE, 1-11)
- AC-MBP (1-11)
- MYELIN BASIC PROTEIN (2-12) ACETYL [MUS MUSCULUS]
- AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS
- CAS:
- 125366-42-9
- MF:
- C53H95N21O18
- MW:
- 1314.45
- Product Categories:
-
- peptide
- Mol File:
- Mol File
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AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-OH Chemical Properties
- Density
- 1.56±0.1 g/cm3(Predicted)
- pka
- 3.20±0.10(Predicted)
- Sequence
- Ac-Ala-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys
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AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-OH Usage And Synthesis
Uses
Ac-MBP 1-11, a short peptide sequence, is the major encephalitogenic epitope in myelin basic protein (MBP)[1].
References
[1] Offner H, et al. Estrogen potentiates treatment with T-cell receptor protein of female mice with experimental encephalomyelitis. J Clin Invest. 2000 May;105(10):1465-72. DOI:10.1172/JCI9213
[2] Adlard K, et al. Immunoregulation of encephalitogenic MBP-NAc1-11-reactive T cells by CD4+ TCR-specific Tcells involves IL-4, IL-10 and IFN-gamma. Autoimmunity. 1999;31(4):237-48. DOI:10.3109/08916939908994069
AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-OHSupplier
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