11(S)-HEPE Chemical Properties

Boiling point:

488.0±45.0 °C(Predicted)

Density 

0.997±0.06 g/cm3(Predicted)

solubility 

0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml

pka

4.75±0.10(Predicted)

11(S)-HEPE Usage And Synthesis

Description

11(S)-HEPE is a monohydroxy fatty acid derived from EPA, theoretically by the action of COX. Although its arachidonate derived congener 11(S)-HETE has been isolated from cultured neutrophils, it is not known if similar incubations with EPA can produce 11(S)-HEPE.¹

Definition

ChEBI: 11S-HEPE is a HEPE.

References

1. Myers, R.F., and Siege, M.I. Differential effects of anti-inflammatory drugs in lipoxygenase and cyclo-oxygenase activities of neutrophils from a reverse passive arthus reaction Biochem. Biophys. Res. Commun. 112,586-594(1983).