N-METHOXY-N-METHYLBENZAMIDE Chemical Properties

Boiling point:

70 °C0.1 mm Hg(lit.)

Density 

1.085 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.533(lit.)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Liquid

color 

Colorless to yellow

Safety Information

WGK Germany 

3

HS Code 

2928009090

MSDS

• Language:English Provider:SigmaAldrich

N-METHOXY-N-METHYLBENZAMIDE Usage And Synthesis

Uses

N-Methoxy-N-methylbenzamide is used to prepare orally bioavailable tetrasubstituted imidazoles as inhibitors of p38 mitogen-activated protein kinase. It is used to synthesize benzofuran and benzothiophene biphenyls as inhibitors of protein tyrosine phosphatase 1B with antihyperglycemic properties.

Uses

N-Methoxy-N-methylbenzamide may be used in the preparation of β-trifluoromethyl enaminones.

Definition

ChEBI: The Weinreb amide of benzoic acid.

General Description

N-Methoxy-N-methylbenzamide is an N,N-disubstituted benzamide. also referred as Weinreb amide., Hydrogen bonding interactions between thioacetamide and N-methoxy-N-methylbenzamide has been investigated using near-infrared absorption spectroscopy. Preparation of N-methoxy-N-methylbenzamide has been reported.

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