Vesicular Stomatitis Virus Nucleoprotein (52-59) Chemical Properties

Sequence

Arg-Gly-Tyr-Val-Tyr-Gln-Gly-Leu

Vesicular Stomatitis Virus Nucleoprotein (52-59) Usage And Synthesis

Uses

H2-D b restricted epitopes VSV Nucleoprotein (52-59) is a 9-mer peptide derived from the nucleoprotein of Vesicular Stomatitis Virus (VSV). H2-D b restricted epitopes VSV Nucleoprotein (52-59) binds to MHC class I molecules and presents itself to CD8+ T cells, thereby activating cytotoxic T lymphocytes (CTLs), which can recognize and kill cells expressing the corresponding antigen. H2-D b restricted epitopes VSV Nucleoprotein (52-59) can be used in the development of CTL vaccines against Ebola virus[1].

References

[1] Herst C V, et al. An effective CTL peptide vaccine for Ebola Zaire Based on Survivors’ CD8+ targeting of a particular nucleocapsid protein epitope with potential implications for COVID-19 vaccine design[J]. Vaccine, 2020, 38(28): 4464-4475. DOI:10.1016/j.vaccine.2020.04.034